Before & after you change the 'FlipFlopWheel' value in Regedit, right-click the 'Device Parameters' folder (the folder that contains the 'FlipFlopWheel' dword) in Regedit & select 'export' & save them as 'Normal Scroll.reg' (Before editing. ie when 'FlipFlopWheel' dword=0) & 'Inverse Scroll.reg' (After editing. ie when 'FlipFlopWheel' dowrd=1) etc respectively.
Then all you have to do is double-click the 'Inverse Scroll.reg' & import it into the registry before playing GTA V & once you're finished playing, do the same with the 'Normal Scroll.reg' to import it into the registry & return the mouse to it's normal scroll direction.
Note: If you install a new mouse you will have to edit the 'Device instance path' (the part like this: VID_17EF&PID_604E\7&16a83a7a&1&0000 etc (it's different for each mouse)) in the '.reg' files, so copy & paste this post somewhere so you can refer to it in future, if you decide to go this route.
The '.reg' files can be opened & edited manually with any text editor (Notepad etc).
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@chonkie Sorry for my late reply. Let me list just the mods I got installed by OpenIV because I have too many scripts mods to list here.
All here are its newest version, no exception, of course with all their own requirements.
FTFR (Fine-Tuned Felony Response)
Gangs of Los Santos - both turf & ped
Dilapidated's heap adjuster (1024MB)
Colored 3D Weapon + Radio Icons 9.0
Realism Enhanced Control System
Realistic Top speed and acceleration (all vehicles)
realistic top speed
With dnSpy you have to make sure you have required assemblies in the same directory as the assembly you are opening (in this case: ScriptHookVDotNet2.dll and iFruitAddon2.dll), and to edit you have to right-click the code area and click Edit Class or Edit Method.
@FelixSG It can be frustrating sometimes, but rebuilding the mods folder helps fix issues at times. I tend to do this each time R* releases a new DLC update and SHV gets updated to match it. This way things should work better without guessing on whether or not there are previous incompatibilities with what was tweaked before the new files were added.