fivem doesnt even replace any game data

at least for me

.dlls can also cause crashing. If the game crashes and the "Grand Theft Auto V has stopped working" pops up, click "view problem details".
If it is a .dll that is causing the crash, it will say so in the "fault module name"

I had this issue before, and it is because of too many add-on cars. Even with limitless gameconfig, there is still a limit. Only way for you to fix it is by combining all your add-on cars into one dlcpack or just simply remove the cars you feel like you don't use often.

Give us a complete list of what you installed?

Install this
https://www.gta5-mods.com/misc/gameconfig-for-patch-1-0-757-2-update-at-each-r-update

I can also give it a go,

i5 6500
8 GB memory
GTX 950 Strix

And nope, I don't have any "problems" with reshade whatsoever.