Honestly, I think the "vram" amount slider thing is not as accurate as people might think. I have a GTX 950 which has 2 GB of vram and I can go beyond that to about 2500-3000 MB without getting significant frame loss, usually about 50-55. It depends on what settings, some which require more vram such as texture quality, will cause stuttering, settings like post processing do not require a lot of vram because it depends on the "clock speed" of the card. So yeah, don't let that vram slider hold you back lol. And no, it doesn't "hurt" the video card in any way, the slider is just there to give you a estimate.